Neuroimaging for COVID-19

Comprehensive, Standardized Neuroradiology Monitoring of COVID-19 Patients

Approximately ⅓ of COVID-19 patients have reported experiencing a range of neurological symptoms including headaches, altered mental states, acute cerebrovascular disease, wide-spread inflammation and edema, and epilepsy. MRI is an important tool in analyzing the extent of any brain damage caused by the virus.

STAGE is designed to provide fast, 5-minute full brain coverage imaging and is collected at a resolution high enough to detect Cerebral Microbleeds and properly reconstruct neurovascular architecture.

Neurological Damage from COVID-19

By combining the information from the susceptibility based contrast outputs of STAGE (SWI, tSWI, SWIM [QSM], R2*map) both very small and very large neurovascular lesions of different make-ups can be visualized while being differentiated from mimics like mineralization (calcium). STAGE can help mitigate the uncertainties surrounding imaging of COVID-19 recovered patients by adequately visualizing a wide range of lesions of various types and compositions.

What do we look for?

  • Cerebral Microbleeds
  • Vascular Malformations/Damage
  • Thrombus/Embolus
  • Subarachnoid Hemorrhage
  • Water Content Changes/Inflammation
  • Stroke/Venuous Oxygenation States
  • Hemorragic Transformation (Acute vs. Chronic)
  • Tissue Type Differentiation (White Matter, Gray Matter, and Cerebrospinal Fluid)
  • Local Changes in Tissue Iron Composition

 Download Use Case

The Benefits of Monitoring With STAGE

STAGE offers the potential to provide excellent characterization and detection of COVID-19 related changes in the brain tissue of recovered patients. STAGE’s efficient acquisition means lesion detection isn’t lost to reducing resolution or increasing slice thickness to save time, and STAGE’s automated reconstruction of multi-parametric outputs means that the limitations of relying on one parametric image set are reduced.

Standardized & Comprehensive Imaging Protocol

  • Reduce the need for patient re-scan with better comprehensive images
  • Receive complete picture of brain characteristics faster than other software
  • Standardized scans ensure consistent and comparable results

Reduce Image Acquisition Time

  • Efficient data point acquisition reduces patient time in magnet while increasing image information depth
  • Counterbalance increased environment sanitation time with shorter MRI scan time

Research-Grade Outputs for Clinical Interpretation

  • Automated post-processing provides improved contrast, quantitative maps and composite images
  • Images are available on the PACS shortly after each MR study is completed and uploaded

Automated Detection of Brain Damage Biomarkers

  • Assess deep gray matter iron level changes typically associated with neurodegenerative diseases
  • Longitudinally monitor hemorrhagic lesions and CMB (hemosiderin deposits) for changes
  • Receive ideal depth of information for AI and data mining by including quantitative

New & Related

All Resources

Traumatic Brain Injury Use Case

Traumatic Brain Injury Use Case

The STAGE protocol is designed to be highly sensitive to the visualization of lesions that may originate from trauma. STAGE has the ability to demonstrate key vascular brain damage which may be missed by conventional or low resolution scans…

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Stroke Detection Use Case

Stroke Detection Use Case

STAGE is designed to benefit imaging and replace standard GRE and SWI in the acute and follow-up setting due to its high sensitivity to blood product lesions in the brain in the form of cerebral microbleeds and thrombus as well as…

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Aging & Dementia Use Case

Aging & Dementia Use Case

STAGE provides a method to visualize brain tissue and neurovascular changes and lesions in the aging brain and Dementia. Phase data is used to reconstruct the source properties…

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